Changing levels of the brain protein KCC2 can alter how reward associations form, reshaping the learning process that links ...

Researchers report October 25 in the journal Neuron that cocaine addiction disrupts the dopamine neurons that govern how we perceive and learn from rewards. Though people with cocaine addiction have ...

Too much screen time — particularly related to social media use in kids, teens and young adults — is a major concern in modern society. Smartphones are ...

Nicotine addiction remains one of the most persistent public health challenges worldwide, driven by changes in the brain that ...

Why do so many people relapse after quitting cocaine? A new study from The Hebrew University reveals that a specific "anti-reward" brain circuit becomes hyperactive during withdrawal-driving ...

New research shows that astrocytes play an active role in nicotine-induced brain changes, challenging the long-held ...

Scientists are testing whether GLP-1 drugs can help to cut cravings for cigarettes, alcohol and opioids — as well as food.

Increasing the levels of chemicals naturally produced in the body called endocannabinoids may thwart the highly addictive nature of opioids such as morphine and oxycodone while maintaining the drugs' ...

A breakup or the loss of a loved one can feel like you're in withdrawal. Their absence can feel like yearning, physical pain — like an addiction no longer fed. And it's that feeling of addiction that ...

More than 48 million Americans have struggled with a substance use disorder (SUD) over the last 12 months. Despite decades of research and treatment interventions, relapse rates remain stubbornly high ...