Oxidative stress occurs when there are high levels of reactive oxygen species (ROS) in the body, that are capable of damaging lipids, proteins, and DNA. Oxidative stress can occur as a result of a ...
Investigation of the association of CTRB2 exon 6 deletion with time to progression and overall survival in pancreatic ductal adenocarcinoma. This is an ASCO Meeting Abstract from the 2025 ASCO ...
p53 is the most famous cancer gene, not least because it's involved in causing over 50% of all cancers. When a cell loses its p53 gene -- when the gene becomes mutated -- it unleashes many processes ...
Pharmacogenomic trial of CPT-11-docetaxel in untreated patients (P) with advanced non small cell lung cancer (NSCLC). A phase II study of the Spanish Lung Cancer Group (SLCG). Correlation with the ...
Since its discovery by Arnold Levine in 1979, the tumor protein p53 has transformed the field of cancer research. p53 signaling plays a key role in regulating the cell cycle, maintaining genome ...